منابع مشابه
Toll-like receptors and NOD-like receptors in rheumatic diseases
The past 10 years have seen the description of families of receptors that drive proinflammatory cytokine production in infection and tissue injury. Two major classes have been examined in the context of inflammatory joint disease--the Toll-like receptors (TLRs) and NOD-like receptors (NLRs). TLRs such as TLR2 and TLR4 are being implicated in the pathology of rheumatoid arthritis, ankylosing spo...
متن کاملToll-like receptors in gastrointestinal diseases.
Innate immune cells - and many other cells - express evolutionarily conserved, germline-encoded receptors that recognize seemingly pathogen-derived ligands (also termed pathogen-associated molecular patterns), thereby allowing the host to perceive infection. Although they were the first to be discovered, Toll-like receptors (TLRs) are not the only pattern recognition receptors. TLRs are unlikel...
متن کاملI-23: Reproduction and Toll Like Receptors(TLRs
Female and male reproductive tracts are of interest sites to study of immune system because they encounter specific infections such as those are sexually transmitted. Furthermore, female reproductive tract is in close contact with allogenic sperms and transmitted microorganisms during intercourse and semi allogenic fetus during pregnancy. In mammals, there are two types of immune responses, the...
متن کاملToll and Toll-like receptors in Drosophila.
The Drosophila Toll receptor controls the immune response to Gram-positive bacteria and fungi by activating a signalling pathway partially conserved throughout evolution. The Drosophila genome encodes eight additional Toll-related receptors, most of which appear to carry out developmental rather than immune functions. One exception may be Toll-9, which shares structural and functional similarit...
متن کاملThe Role of Toll-Like Receptors in Breast Cancer
Breast cancer is highly prevalent worldwide. Treatment of this disease is a major global public health problem; therefore, numerous studies have explored new molecular profile helping for breast cancer therapy. Different risk factors are attributed to breast cancer; however, chronic inflammation and immune regulation are highly essential. Various molecules impact this context, including toll-li...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Immunopharmacology
سال: 2011
ISSN: 1567-5769
DOI: 10.1016/j.intimp.2011.08.010